Metagenomic analysis of gut microbial communities from a Central Asian population.

ABSTRACT:

Objective

Changes in the gut microbiota are increasingly recognised to be involved in many diseases. This ecosystem is known to be shaped by many factors, including climate, geography, host nutrition, lifestyle and medication. Thus, knowledge of varying populations with different habits is important for a better understanding of the microbiome.

Design

We therefore conducted a metagenomic analysis of intestinal microbiota from Kazakh donors, recruiting 84 subjects, including male and female healthy subjects and metabolic syndrome (MetS) patients aged 25-75 years, from the Kazakh administrative centre, Astana. We characterise and describe these microbiomes, the first deep-sequencing cohort from Central Asia, in comparison with a global dataset (832 individuals from five countr

SUBMITTER: Kushugulova A 

PROVIDER: S-EPMC6067398 | biostudies-literature | 2018 Jul

REPOSITORIES: biostudies-literature