Changing use of antidiabetic drugs in the UK: trends in prescribing 2000-2017.

ABSTRACT:

Objectives

Guidelines for the use of drugs for type 2 diabetes mellitus (T2DM) have changed since 2000, and new classes of drug have been introduced. Our aim was to describe how drug choice at initiation and first stage of intensification have changed over this period, and to what extent prescribing was in accord with clinical guidelines, including adherence to recommendations regarding kidney function.

Design

Repeated cross-sectional study.

Setting

UK electronic primary care health records from the Clinical Practice Research Datalink.

Participants

Adults initiating treatment with a drug for T2DM between January 2000 and July 2017.

Primary and secondary outcome measures

The primary outcomes were the proportion of each class of T2DM drug prescribed for in

SUBMITTER: Wilkinson S 

PROVIDER: S-EPMC6067400 | biostudies-literature | 2018 Jul

REPOSITORIES: biostudies-literature