Triacetin Enhances Levels of Acrolein, Formaldehyde Hemiacetals, and Acetaldehyde in Electronic Cigarette Aerosols.

ABSTRACT: The health effects of inhaled electronic cigarette (e-cigarette) flavoring compounds are largely unknown. Earlier reports of their chemical reactivity have been conflicting, with some claiming, for example, that the degradation of flavoring chemicals in e-cigarettes to aldehydes is statistically insignificant. It is thus important to understand how these molecules react to afford enhanced aerosol products. The purpose of the current study was to investigate the origin of formaldehyde, acrolein, and acetaldehyde in e-cigarettes that contain the popular additive, triacetin (TA). By using ¹³C labeling and a combination of ¹H NMR and ¹³C NMR, we were able to identify that ester hydrolysis of TA occurs to form acetic acid (HOAc) during aerosolization. The releas

SUBMITTER: Vreeke S 

PROVIDER: S-EPMC6068691 | biostudies-literature | 2018 Jul

REPOSITORIES: biostudies-literature