Systematic review of the impact of breast-conserving surgery on cancer outcomes of multiple ipsilateral breast cancers.

ABSTRACT:

Background

The clinical effectiveness of treating ipsilateral multifocal (MF) and multicentric (MC) breast cancers using breast-conserving surgery (BCS) compared with the standard of mastectomy is uncertain. Inconsistencies relate to definitions, incidence, staging and intertumoral heterogeneity. The primary aim of this systematic review was to compare clinical outcomes after BCS versus mastectomy for MF and MC cancers, collectively defined as multiple ipsilateral breast cancers (MIBC).

Methods

Comprehensive electronic searches were undertaken to identify complete papers published in English between May 1988 and July 2015, primarily comparing clinical outcomes of BCS and mastectomy for MIBC. All study designs were included, and studies were appraised critically using the New

SUBMITTER: Winters ZE 

PROVIDER: S-EPMC6069349 | biostudies-literature | 2018 Aug

REPOSITORIES: biostudies-literature