HIV and TB co-infection in the ART era: CD4 count distributions and TB case fatality in Cape Town.

ABSTRACT:

Background

In Cape Town, the roll-out of antiretroviral therapy (ART) has increased over the last decade with an estimated coverage of 63% of HIV- positive patients in 2013. The influence of ART on the characteristics of the population of HIV-positive patients presenting to the primary care TB programme is unknown. In this study, we examined trends in CD4 count distribution, ART usage and treatment outcomes among HIV-positive TB patients in Cape Town from 2009 to 2013.

Methods

Data from the electronic TB register on all newly registered drug-sensitive TB patients ≥18 years were analyzed retrospectively. Descriptive statistics were used to compare baseline characteristics, the CD4 count distribution and TB treatment outcomes both by year of treatment and ART status at the sta

SUBMITTER: Kaplan R 

PROVIDER: S-EPMC6069570 | biostudies-literature | 2018 Jul

REPOSITORIES: biostudies-literature