High Ghrelin Level Predicts the Curve Progression of Adolescent Idiopathic Scoliosis Girls.

ABSTRACT:

Background

Adolescent idiopathic scoliosis (AIS) is common deformity with unknown cause. Previous studies have suggested the abnormal serum leptin and ghrelin level in AIS girls. The aim of present study was to evaluate whether the serum leptin and ghrelin level could serve as risk factor in predicting the curve progression in AIS girls. The associations between them and the physical characteristics were also investigated.

Materials and methods

Circulating leptin and ghrelin levels from 105 AIS girls and 40 age-matched non-AIS girls were examined by enzyme-linked immunosorbent assay. The correlations between ghrelin and leptin levels and growth-related parameters (age, weight, corrected height, corrected BMI, main Cobb angle, and Risser sign) were analyzed in AIS group. Mult

SUBMITTER: Yu HG 

PROVIDER: S-EPMC6069699 | biostudies-literature | 2018

REPOSITORIES: biostudies-literature