Normoalbuminuric kidney impairment in patients with T1DM: insights from annals initiative.

ABSTRACT:

Background

We described, in a large sample of patients with type 1 diabetes mellitus (T1DM) and GFR ≤ 60 mL/min/1.73 m² (with or without albuminuria), the differences in the clinical features associated with the two different chronic kidney disease phenotypes and we investigated, in a subset of patients, the modulating role of albuminuria on kidney disease progression.

Methods

Clinical data of 1395 patients with T1DM were extracted from electronic medical records.

Results

Albuminuria was detected in 676 (48.5%) patients, with the remaining 719 (51.5%) patients having normoalbuminuric renal impairment. Those with albuminuria showed an evident worse cardiovascular risk profile as compared to patients with normoalbuminuria. A subgroup of 582 patients was follo

SUBMITTER: Lamacchia O 

PROVIDER: S-EPMC6069993 | biostudies-literature | 2018

REPOSITORIES: biostudies-literature