Study the Features of 57 Confirmed CRISPR Loci in 38 Strains of Staphylococcus aureus.

ABSTRACT: Staphylococcus aureus is a foodborne pathogen that causes food contamination and food poisoning, which poses great harm to health, agriculture and other hosts. Clustered regularly interspaced short palindromic repeats (CRISPR) are a recently discovered bacterial immune system that resists foreign genes such as phage DNA. This system inhibits the transfer of specific movable genetic elements that match the CRISPR spacer sequences, thereby preventing the spread of drug-resistant genes between pathogens. In this study, 57 CRISPR loci were screened from 38 strains of S. aureus based on the CRISPR database, and bioinformatics tools were used to investigate the structural features and potential functions of S. aureus CRISPR loci. The results showed that most strains containe

SUBMITTER: Zhao X 

PROVIDER: S-EPMC6070637 | biostudies-literature | 2018

REPOSITORIES: biostudies-literature