CapC, a Novel Autotransporter and Virulence Factor of Campylobacter jejuni.

ABSTRACT: Campylobacter jejuni is recognized as an important causative agent of bacterial gastroenteritis in the developed world. Despite the identification of several factors contributing to infection, characterization of the virulence strategies employed by C. jejuni remains a significant challenge. Bacterial autotransporter proteins are a major class of secretory proteins in Gram-negative bacteria, and notably, many autotransporter proteins contribute to bacterial virulence. The aim of this study was to characterize the C. jejuni 81116 C8J_1278 gene (capC), predicted to encode an autotransporter protein, and examine the contribution of this factor to virulence of C. jejuni The predicted CapC protein has a number of features that are consistent with autotransport

SUBMITTER: Mehat JW 

PROVIDER: S-EPMC6070749 | biostudies-literature | 2018 Aug

REPOSITORIES: biostudies-literature