Nanostructured Hydrogels by Blend Electrospinning of Polycaprolactone/Gelatin Nanofibers.

ABSTRACT: Nanofibrous membranes based on polycaprolactone (PCL) have a large potential for use in biomedical applications but are limited by the hydrophobicity of PCL. Blend electrospinning of PCL with other biomedical suited materials, such as gelatin (Gt) allows for the design of better and new materials. This study investigates the possibility of blend electrospinning PCL/Gt nanofibrous membranes which can be used to design a range of novel materials better suited for biomedical applications. The electrospinnability and stability of PCL/Gt blend nanofibers from a non-toxic acid solvent system are investigated. The solvent system developed in this work allows good electrospinnable emulsions for the whole PCL/Gt composition range. Uniform bead-free nanofibers can easily be produced, and the resulti

SUBMITTER: Daelemans L 

PROVIDER: S-EPMC6070828 | biostudies-literature | 2018 Jul

REPOSITORIES: biostudies-literature