Determination of the Role of Microcystis aeruginosa in Toxin Generation Based on Phosphoproteomic Profiles.

ABSTRACT: Microcystis aeruginosa is the most common species responsible for toxic cyanobacterial blooms and is considered a significant contributor to the production of cyanotoxins, particularly the potent liver toxins called microcystins. Numerous studies investigating Microcystis spp. blooms have revealed their deleterious effects in freshwater environments. However, the available knowledge regarding the global phosphoproteomics of M. aeruginosa and their regulatory roles in toxin generation is limited. In this study, we conducted comparative phosphoproteomic profiling of non-toxic and toxin-producing strains of M. aeruginosa. We identified 59 phosphorylation sites in 37 proteins in a non-toxic strain and 26 phosphorylation sites in 18 proteins in a toxin-producing stra

SUBMITTER: Qu J 

PROVIDER: S-EPMC6070999 | biostudies-literature | 2018 Jul

REPOSITORIES: biostudies-literature