Identification and Characterization of Long Noncoding RNAs in Ovine Skeletal Muscle.

ABSTRACT: Long noncoding RNAs (lncRNAs) are increasingly being recognized as key regulators in many cellular processes. However, few reports of them in livestock have been published. Here, we describe the identification and characterization of lncRNAs in ovine skeletal muscle. Eight libraries were constructed from the gastrocnemius muscle of fetal (days 85 and 120), newborn and adult Texel and Ujumqin sheep. The 2002 identified transcripts shared some characteristics, such as their number of exons, length and distribution. We also identified some coding genes near these lncRNA transcripts, which are particularly associated with transcriptional regulation- and development-related processes, suggesting that the lncRNAs are associated with muscle development. In addition, in pairwise comparisons betwee

SUBMITTER: Li Q 

PROVIDER: S-EPMC6071021 | biostudies-literature | 2018 Jul

REPOSITORIES: biostudies-literature