Association between homocysteine level and the risk of diabetic retinopathy: a systematic review and meta-analysis.

ABSTRACT:

Background

Previous studies have demonstrated that elevated homocysteine (Hcy) level represents an independent risk factor for macrovascular disease. However, the relationship between hyperhomocysteinemia and the progression of diabetic retinopathy in patients remains controversial. Hence, the purpose of this systematic review and meta-analysis was to explore any potential association between Hcy and the risk of diabetic retinopathy.

Methods

PubMed, Embase, and the Cochrane Library databases were searched to screen studies that fulfilled the inclusion criteria from date of database inception to November 2017. The summary odds ratio (OR) with 95% confidence intervals (CIs) was used to calculate the pooled effect estimate for the relationship between Hcy and diabetic retinopat

SUBMITTER: Lei X 

PROVIDER: S-EPMC6071377 | biostudies-literature | 2018

REPOSITORIES: biostudies-literature