Smaller kidney size at birth in South Asians: findings from the Born in Bradford birth cohort study.

ABSTRACT:

Background

Rates of advanced chronic kidney disease and renal replacement therapy are higher in South Asian than in white British populations. Low birth weight is also more frequent in South Asian populations and has been associated with increased risks of kidney disease, perhaps due to a reduced nephron endowment.

Methods

Using ultrasound scans at 34 weeks of gestation, we measured fetal kidney dimensions (transverse and anteroposterior diameters, length and circumference) and derived volume in a random sample of 872 white British and 715 South Asian participants in the Born in Bradford cohort study. Kidney measurements were compared between ethnic groups.

Results

Birth weight for gestational age at 40 weeks was 200 g less in South Asian babies compared with white Br

SUBMITTER: Roderick PJ 

PROVIDER: S-EPMC6071385 | biostudies-literature | 2016 Mar

REPOSITORIES: biostudies-literature