FusC, a member of the M16 protease family acquired by bacteria for iron piracy against plants.

ABSTRACT: Iron is essential for life. Accessing iron from the environment can be a limiting factor that determines success in a given environmental niche. For bacteria, access of chelated iron from the environment is often mediated by TonB-dependent transporters (TBDTs), which are β-barrel proteins that form sophisticated channels in the outer membrane. Reports of iron-bearing proteins being used as a source of iron indicate specific protein import reactions across the bacterial outer membrane. The molecular mechanism by which a folded protein can be imported in this way had remained mysterious, as did the evolutionary process that could lead to such a protein import pathway. How does the bacterium evolve the specificity factors that would be required to select and import a protein encoded on anothe

SUBMITTER: Grinter R 

PROVIDER: S-EPMC6071955 | biostudies-literature | 2018 Aug

REPOSITORIES: biostudies-literature