Independent association between subjective cognitive decline and frailty in the elderly.

ABSTRACT:

Background

The relationship between subjective cognitive decline and frailty, two components of the so-called reversible cognitive frailty, in the elderly remains unclear. This study aims to elucidate whether this association exists, independent of confounding factors such as nutritional status, kidney function, inflammation, and insulin resistance.

Methods

2386 participants (≥ 65 years of age) selected from the Healthy Aging Longitudinal Study in Taiwan (HALST) study. Fried frailty phenotype was adopted to quantify frailty status. We classified cognitive status into two categories-subjective cognitive decline (SCD), and normal cognition-and used polytomous logistic regressions to investigate the associations between SCD and frailty.

Results

There were 188 (7.88%), 12

SUBMITTER: Hsieh TJ 

PROVIDER: S-EPMC6072005 | biostudies-literature | 2018

REPOSITORIES: biostudies-literature