Improved glucose metabolism by Eragrostis tef potentially through beige adipocyte formation and attenuating adipose tissue inflammation.

ABSTRACT:

Background

Teff is a staple food in Ethiopia that is rich in dietary fiber. Although gaining popularity in Western countries because it is gluten-free, the effects of teff on glucose metabolism remain unknown.

Aim

To evaluate the effects of teff on body weight and glucose metabolism compared with an isocaloric diet containing wheat.

Results

Mice fed teff weighed approximately 13% less than mice fed wheat (p < 0.05). The teff-based diet improved glucose tolerance compared with the wheat group with normal chow but not with a high-fat diet. Reduced adipose inflammation characterized by lower expression of TNFα, Mcp1, and CD11c, together with higher levels of cecal short chain fatty acids such as acetate, compared with the control diet containing wheat after 14 weeks of d

SUBMITTER: Lemecha M 

PROVIDER: S-EPMC6072038 | biostudies-literature | 2018

REPOSITORIES: biostudies-literature