Vitamin D and Uterine Fibroids-Review of the Literature and Novel Concepts.

ABSTRACT: This article provides a detailed review of current knowledge on the role of vitamin D and its receptor in the biology and management of uterine fibroids (UFs). Authors present ideas for future steps in this area. A literature search was conducted in PubMed using the following key words: "uterine fibroid" and "vitamin D". The results of the available studies, published in English from January 2002 up to April 2018, have been discussed. Vitamin D is a group of steroid compounds with a powerful impact on many parts of the human body. This vitamin is believed to regulate cell proliferation and differentiation, inhibit angiogenesis, and stimulate apoptosis. Nowadays, hypovitaminosis D is believed to be a major risk factor in the development of UFs. In many studies vitamin D appears to be a powe

SUBMITTER: Ciebiera M 

PROVIDER: S-EPMC6073230 | biostudies-literature | 2018 Jul

REPOSITORIES: biostudies-literature