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Procerus Sign: Mechanism, Clinical Usefulness, and Controversies.


ABSTRACT: This sign is observed in atypical parkinsonism mainly in Progressive Supranuclear Palsy. The exact mechanism of this sign is not clear but the contraction of the Corrugator Supercilii muscle is the most important factor for the generation of vertical forehead creases. Though the wrinkling of forehead is a complex phenomenon involving multiple muscles but the 'Corrugator sign' would be a better term to describe this phenomenon. Despite the controversies regarding the mechanism and nomenclature, the 'Procerus sign' remains an important clinical clue for early Progressive Supranuclear palsy.

SUBMITTER: Bhattacharjee S 

PROVIDER: S-EPMC6073967 | biostudies-literature | 2018 Apr-Jun

REPOSITORIES: biostudies-literature

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Procerus Sign: Mechanism, Clinical Usefulness, and Controversies.

Bhattacharjee Shakya S  

Annals of Indian Academy of Neurology 20180401 2


This sign is observed in atypical parkinsonism mainly in Progressive Supranuclear Palsy. The exact mechanism of this sign is not clear but the contraction of the Corrugator Supercilii muscle is the most important factor for the generation of vertical forehead creases. Though the wrinkling of forehead is a complex phenomenon involving multiple muscles but the 'Corrugator sign' would be a better term to describe this phenomenon. Despite the controversies regarding the mechanism and nomenclature, t  ...[more]

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