Reflections on translation: Views of participants in a multisite Canadian CCSVI clinical trial.

ABSTRACT:

Background

We sought to characterize the perspectives of participants in Canada's phase I/II chronic cerebrospinal venous insufficiency (CCSVI) clinical trial prior to and after the disclosure of trial results.

Methods

This was a researcher-administered survey of individuals who participated in Canada's CCSVI trial (Clincialtrials.gov, NCT01864941) about their (1) motivations for participating, (2) understanding of the trial process, and (3) perspectives on the social value of the trial.

Results

A total of 63 participants completed the survey. Participants were motivated to participate by altruism (mean score = 4.56 out of 5) and a desire to access the intervention in Canada (mean score = 3.63 out of 5). Many participants expected medical benefits, such as partial dis

SUBMITTER: Benjaminy S 

PROVIDER: S-EPMC6075987 | biostudies-literature | 2018 Jun

REPOSITORIES: biostudies-literature