Prevalence of and risk factors for cerebral microbleeds in a general Japanese elderly community.

ABSTRACT:

Background

We investigated the prevalence of and risk factors for cerebral microbleeds (CMBs) in a cross-sectional study of a general population of Japanese elderly.

Methods

In 2012, brain MRI scanning at 1.5T and comprehensive health examination were conducted for 1281 residents aged 65 years or older. CMBs were defined as ovoid hypointensity lesions less than 10 mm in diameter on T2*-weighted images and classified into deep/infratentorial or lobar CMBs. Age- and sex-specific and overall prevalence of CMBs were estimated, and the associations of traditional cardiovascular risk factors and APOE polymorphism with the presence of CMBs were examined using a logistic regression analysis.

Results

The crude prevalences of total, deep/infratentorial, and lobar CMBs we

SUBMITTER: Yubi T 

PROVIDER: S-EPMC6075994 | biostudies-literature | 2018 Jun

REPOSITORIES: biostudies-literature