Ontology highlight
ABSTRACT:
SUBMITTER: Stucchi R
PROVIDER: S-EPMC6077247 | biostudies-literature | 2018 Jul
REPOSITORIES: biostudies-literature
Cell reports 20180701 3
Tight regulation of neuronal transport allows for cargo binding and release at specific cellular locations. The mechanisms by which motor proteins are loaded on vesicles and how cargoes are captured at appropriate sites remain unclear. To better understand how KIF1A-driven dense core vesicle (DCV) transport is regulated, we identified the KIF1A interactome and focused on three binding partners, the calcium binding protein calmodulin (CaM) and two synaptic scaffolding proteins: liprin-α and TANC2 ...[more]