Characteristics of Sinus Fungus Ball: A Unique Form of Rhinosinusitis.

ABSTRACT:

Objective

The purpose of this study was to investigate the characteristics of this unique form of rhinosinusitis.

Methods

Ninety-one patients with sinus fungus balls were evaluated for clinical characteristics. Nasal tissues obtained from 38 patients with sinus fungus ball, along with 26 controls were used for histopathological, cytokines/chemokines, western blotting, and genetic analyses.

Results

Patients with fungus balls had significantly more females and their age was older. The presentation of fungus ball was predominantly unilateral (97.8%). Thirty-three patients (36.3%) had risk factors for fungal infection. Macrophage and neutrophil dominated cellular infiltration was found in nasal tissues of fungus ball patients. A tendency of reduced tight junction staining

SUBMITTER: Jiang RS 

PROVIDER: S-EPMC6077877 | biostudies-literature | 2018

REPOSITORIES: biostudies-literature