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ABSTRACT: Background
Mobility impairments have substantial physical and mental health consequences, resulting in diminished quality of life. Most studies on the health economic consequences of mobility limitations focus on short-term implications.Objectives
To examine the long-term value of improving mobility in older adults.Methods
Our six-step approach used clinical trial data to calibrate mobility improvements and estimate health economic outcomes using a microsimulation model. First, we measured improvement in steps per day calibrated with clinical trial data examining hylan G-F 20 viscosupplementation treatment. Second, we created a cohort of patients 51 years and older with osteoarthritis. In the third step, we estimated their baseline quality of life. Fourth, we transl
SUBMITTER: Kabiri M
PROVIDER: S-EPMC6078098 | biostudies-literature | 2018 Jul
REPOSITORIES: biostudies-literature