Protocol for the study of cervical cancer screening technologies in HIV-infected women living in Rwanda.

ABSTRACT:

Introduction

The optimal method(s) for screening HIV-infected women, especially for those living in sub-Saharan Africa, for cervical precancer and early cancer has yet to be established.

Methods and analysis

A convenience sample of >5000 Rwandan women, ages 30-54 years and living with HIV infection, is being consented and enroled into a cross-sectional study of cervical cancer screening strategies. Participants are completing an administered short risk factor questionnaire and being screened for high-risk human papillomavirus (hrHPV) using the Xpert HPV assay (Cepheid, Sunnyvale, California, USA), unaided visual inspection after acetic acid (VIA) and aided VIA using the Enhanced Visual Assessment (EVA) system (Mobile ODT, Tel Aviv, Israel). Women positive for hrHPV and/or by

SUBMITTER: Murenzi G 

PROVIDER: S-EPMC6078254 | biostudies-literature | 2018 Aug

REPOSITORIES: biostudies-literature