The influence of hormone therapy with drospirenone-estradiol on endometrioid type endometrial cancer patients.

ABSTRACT:

Objective

To determine whether drospirenone/estradiol (DRSP/E2) has an adverse effect on clinical outcomes in surgically staged International Federation of Gynecology and Obstetrics (FIGO) stage I/II endometrial cancer (EC) patients.

Methods

In a retrospective case-controlled study, 58 women with EC who had received DRSP/E2 postoperatively were compared with 116 women who had not. And, oncologic safety of postoperative hormone therapy with DRSP/E2 in EC survivors were compared between the 2 groups after propensity score matching using a logistic regression model.

Results

The median ages were 47.7 years and 53.6 years for the study and the control groups, respectively (p<0.001). The study group had similar parity (p=0.71), lower body mass index (p=0.03) and more premen

SUBMITTER: Lim S 

PROVIDER: S-EPMC6078887 | biostudies-literature | 2018 Sep

REPOSITORIES: biostudies-literature