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Researches of Epigenetic Epidemiology for Infections and Radiation as Carcinogen.


ABSTRACT: In recent years, a number of studies have been reported on the various types of cancer arising from epigenetic alterations, including reports that these epigenetic alterations occur as a result of radiation exposure or infection. Thyroid cancer and breast cancer, in particular, have high cancer burden, and it has been confirmed that radiation exposure or onco-viral infection are linked to increased risk of development of these two types of cancer, respectively. Thus, the environment-epigenetic alteration-cancer occurrence (EEC) hypothesis has been suggested. This paper reviews the trends in research supporting this hypothesis for radiation exposure and onco-viral infection. If more evidences accumulate for the EEC hypothesis from future research, those findings may greatly aid in the preve

SUBMITTER: Bae JM 

PROVIDER: S-EPMC6078917 | biostudies-literature | 2018 Jul

REPOSITORIES: biostudies-literature