Image-enhanced endoscopy is specific for the diagnosis of non-erosive gastroesophageal reflux disease.

ABSTRACT: OBJECTIVES:We assessed the performance characteristics of image-enhanced endoscopy with i-Scan or narrow band imaging (NBI) in patients with non-erosive gastroesophageal reflux disease (GERD) compared to controls without heartburn. MATERIAL AND METHODS:Image-enhanced endoscopic findings of vascularity at the squamocolumnar junction, distal esophageal micro-erosions, and non-round pit pattern at the squamocolumnar junction were assessed in cases (heartburn not responsive to PPIs, positive results on validated GERD questionnaire, no esophageal erosions, esophageal biopsies with histologic evidence of GERD (basal cell hyperplasia, elongation of papillae and dilation of intercellular spaces all required)) and in controls (no GERD symptoms or esophageal erosions). RESULTS:Twenty cases and 60 co

SUBMITTER: Parikh ND 

PROVIDER: S-EPMC6080852 | biostudies-literature | 2018 Mar

REPOSITORIES: biostudies-literature