Identification of high-risk plaque features in intracranial atherosclerosis: initial experience using a radiomic approach.

ABSTRACT:

Objectives

To evaluate a quantitative radiomic approach based on high-resolution magnetic resonance imaging (HR-MRI) to differentiate acute/sub-acute symptomatic basilar artery plaque from asymptomatic plaque.

Methods

Ninety-six patients with basilar artery stenosis underwent HR-MRI between January 2014 and December 2016. Patients were scanned with T1- and T2-weighted imaging, as well as T1 imaging following gadolinium-contrast injection (CE-T1). The stenosis value, plaque area/burden, lumen area, minimal luminal area (MLA), intraplaque haemorrhage (IPH), contrast enhancement ratio and 94 quantitative radiomic features were extracted and compared between acute/sub-acute and asymptomatic patients. Multi-variate logistic analysis and a random forest model were used to evaluate

SUBMITTER: Shi Z 

PROVIDER: S-EPMC6081255 | biostudies-literature | 2018 Sep

REPOSITORIES: biostudies-literature