No evidence of association of oxytocin polymorphisms with breastfeeding in 2 independent samples.

ABSTRACT: Oxytocin has an important function in breastfeeding via its role in the milk ejection reflex and in attachment and bonding processes. Genetic factors account for a significant part of the individual differences in breastfeeding behavior. OXT and OXTR have been proposed as gene candidates for breastfeeding. Previous studies have focused on certain single-nucleotide polymorphisms (SNPs) within these genes, finding null or inconsistent results. The present study analyses the associations between a wide coverage of polymorphisms in OXT and OXTR and breastfeeding duration from 2 large and independent unselected samples comprising a total of 580 and 2112 female twin mothers from the Murcia Twin Registry (Spain) and QIMR Berghofer Medical Research Institute (Australia), respectively. A total of 1

SUBMITTER: Colodro-Conde L 

PROVIDER: S-EPMC6081273 | biostudies-literature | 2018 Sep

REPOSITORIES: biostudies-literature