Diagnostic test results in primary CNS vasculitis: A systematic review of published cases.

ABSTRACT:

Background

Primary CNS vasculitis (PCNSV) can be diagnosed using cerebral angiography or histopathology combined with clinical features. The original diagnostic criteria, which weigh each test equally, have not been validated. Limited sensitivity and specificity for biopsy and angiography are recognized. We systematically reviewed results of diagnostic tests performed in patients with an ultimate diagnosis of PCNSV.

Methods

We searched the OVID Medline database and bibliographies for original cases of PCNSV. We recorded demographics, diagnostic tests used, and assessed agreement between angiography and biopsy when both tests were performed. We also recorded MRI and CSF results.

Results

We found 701 original cases with PCNSV diagnosed with angiography or pathology. A t

SUBMITTER: McVerry F 

PROVIDER: S-EPMC6081966 | biostudies-literature | 2017 Jun

REPOSITORIES: biostudies-literature