3D Printed Microfluidic Features Using Dose Control in X, Y, and Z Dimensions.

ABSTRACT: Interest has grown in recent years to leverage the possibilities offered by three-dimensional (3D) printing, such as rapid iterative changes; the ability to more fully use 3D device volume; and ease of fabrication, especially as it relates to the creation of complex microfluidic devices. A major shortcoming of most commercially available 3D printers is that their resolution is not sufficient to produce features that are truly microfluidic (<100 × 100 μm²). Here, we test a custom 3D printer for making ~30 μm scale positive and negative surface features, as well as positive and negative features within internal voids (i.e., microfluidic channels). We found that optical dosage control is essential for creating the smallest microfluidic features (~30 µm wide for ridges, ~20 µm wide for trenche

SUBMITTER: Beauchamp MJ 

PROVIDER: S-EPMC6082287 | biostudies-literature | 2018 Jun

REPOSITORIES: biostudies-literature