Ambient Air Currents Activate Corneal Nerves During Ocular Desiccation in Rats: Simultaneous Recordings of Neural Activity and Corneal Temperature.

ABSTRACT:

Purpose

Previously we found two types of corneal neurons that we hypothesized to play an important role in tearing. One type is called low threshold-cold sensitive plus dry sensitive (LT-CS + DS), and the other is termed high threshold-cold sensitive plus dry sensitive (HT-CS + DS). The present study examined critical stimuli influencing the activity of these neurons to elucidate environmental factors that may trigger this ocular reflex.

Methods

Single corneal neurons were extracellularly recorded from the trigeminal ganglia in response to ocular stimuli that mimic environmental conditions one encounters in daily life. They included an ocular desiccation and slight air currents and were presented while simultaneously monitoring the ocular surface temperatures (OST) in rats.<

SUBMITTER: Hirata H 

PROVIDER: S-EPMC6082328 | biostudies-literature | 2018 Aug

REPOSITORIES: biostudies-literature