Cognitive function and patient-reported memory problems after radiotherapy for cancers at the skull base: A cross-sectional survivorship study using the Telephone Interview for Cognitive Status and the MD Anderson Symptom Inventory-Head and Neck Module.

ABSTRACT:

Background

Using patient-reported and objective assessment tools, we sought to quantify cognitive symptoms and objective cognitive dysfunction in patients irradiated for skull base cancer.

Methods

Participants were assessed using the Telephone Interview for Cognitive Status (TICS) and the MD Anderson Symptom Inventory-Head and Neck module (MDASI-HN), with subsequent analysis.

Results

Of the 122 participants analyzed, the majority (63%) had no frank detectable cognitive impairment by TICS, with frank impairment in 6%. Overall, mean patient-reported problems with memory (MDASI_memory ) was 3.3 (SD ±2.66). On recursive partition analysis, the MDASI_memory cutoff point of ≥5 was associated with detectable cognitive impairment by TICS (logworth 1.69; P

SUBMITTER: Hansen CC 

PROVIDER: S-EPMC6082378 | biostudies-literature | 2017 Oct

REPOSITORIES: biostudies-literature