Social cognition moderates the relationship between neurocognition and community functioning in bipolar disorder.

ABSTRACT:

Background

Schizophrenia (SZ) studies suggest that neurocognition predicts functional outcome and that social cognition mediates this relationship. Bipolar disorder (BD) patients also have cognitive, social, and functional impairments but the relationship among these factors in BD is not well established. We assessed whether social cognition modulates the influence of neurocognition on community functioning in BD, as found in SZ.

Methods

200 BD patients and 49 healthy controls (HC) were administered and compared on a battery of tests assessing neurocognition, social cognition, and community functioning. We conducted a series of regression analyses to investigate potential mediation or moderation of social cognition on the relationship between neurocognition and community fun

SUBMITTER: Ospina LH 

PROVIDER: S-EPMC6082404 | biostudies-literature | 2018 Aug

REPOSITORIES: biostudies-literature