Clinical and ultrasonographic predictors for achieving minimal disease activity in patients with psoriatic arthritis: the UPSTREAM (Ultrasound in PSoriatic arthritis TREAtMent) prospective observational study protocol.

ABSTRACT:

Introduction

Psoriatic arthritis (PsA) occurs in 10%-15% of people with psoriasis and accounts for 10%-20% of early arthritis clinics referral. Only a few prognostic factors of therapeutic response in patients with PsA have been identified. In the last years, the role of imaging has grown up and the European League Against Rheumatism recognised that ultrasound (US) has higher sensitivity than clinical examination to detect inflammatory disease activity. The aims of the Ultrasound in PSoriatic arthritis TREAtMent (UPSTREAM) study are to integrate clinic and US in order to inform whether US has provide an added prognostic value in PsA.

Methods and analysis

UPSTREAM is an observational prospective cohort study enrolling patients with PsA having clinically active joint disease a

SUBMITTER: Canzoni M 

PROVIDER: S-EPMC6082450 | biostudies-literature | 2018 Jul

REPOSITORIES: biostudies-literature