Interrupted time-series analysis of the impact of generic market entry of antineoplastic products in China.

ABSTRACT:

Objectives

The rapid growth of pharmaceutical costs is a major healthcare issue all over the world. The high prices of new drugs, especially those for cancer, are also a concern for stakeholders. Generic drugs are a major price-reducing opportunity and provide more societal value. The aim of this research is to analyse the impact of generic entry on the volume and cost of antineoplastic agents in China.

Methods

An interrupted time-series design examined monthly sales of three antineoplastic drugs (capecitabine, decitabine, imatinib) from 699 public hospitals during January 2011 to June 2016. The first generic entry times (December 2013, December 2012, August 2013, respectively) were regarded as the intervention time points. We estimated changes in volume and cost following t

SUBMITTER: Guan X 

PROVIDER: S-EPMC6082476 | biostudies-literature | 2018 Jul

REPOSITORIES: biostudies-literature