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Impact of comorbid conditions on outcomes of hip and knee replacement surgery: a systematic review and meta-analysis.


ABSTRACT:

Objective

To systematically perform a meta-analysis of the association between different comorbid conditions on safety (short-term outcomes) and effectiveness (long-term outcomes) in patients undergoing hip and knee replacement surgery.

Design

Systematic review and meta-analysis.

Methods

Medline, Embase and CINAHL Plus were searched up to May 2017. We included all studies that reported data to allow the calculation of a pooled OR for the impact of 11 comorbid conditions on 10 outcomes (including surgical complications, readmissions, mortality, function, health-related quality of life, pain and revision surgery). The quality of included studies was assessed using a modified Newcastle-Ottawa Scale. Continuous outcomes were converted to ORs using the Hasselblad and Hedge

SUBMITTER: Podmore B 

PROVIDER: S-EPMC6082478 | biostudies-literature | 2018 Jul

REPOSITORIES: biostudies-literature