Effect of Tamsulosin on Passage of Symptomatic Ureteral Stones: A Randomized Clinical Trial.

ABSTRACT:

Importance

Urinary stone disease is a common presentation in the emergency department, and α-adrenergic receptor blockers, such as tamsulosin, are commonly used to facilitate stone passage.

Objective

To determine if tamsulosin promotes the passage of urinary stones within 28 days among emergency department patients.

Design, setting, and participants

We conducted a double-blind, placebo-controlled clinical trial from 2008 to 2009 (first phase) and then from 2012 to 2016 (second phase). Participants were followed for 90 days. The first phase was conducted at a single US emergency department; the second phase was conducted at 6 US emergency departments. Adult patients were eligible to participate if they presented with a symptomatic urinary stone in the ureter less than

SUBMITTER: Meltzer AC 

PROVIDER: S-EPMC6082698 | biostudies-literature | 2018 Aug

REPOSITORIES: biostudies-literature