Miscarriage and stillbirth following maternal Zika virus infection in nonhuman primates.

ABSTRACT: Zika virus (ZIKV) infection is associated with congenital defects and pregnancy loss. Here, we found that 26% of nonhuman primates infected with Asian/American ZIKV in early gestation experienced fetal demise later in pregnancy despite showing few clinical signs of infection. Pregnancy loss due to asymptomatic ZIKV infection may therefore be a common but under-recognized adverse outcome related to maternal ZIKV infection.

SUBMITTER: Dudley DM 

PROVIDER: S-EPMC6082723 | biostudies-literature | 2018 Aug

REPOSITORIES: biostudies-literature