Aberrant Neural Activation Underlying Idiom Comprehension in Korean Children with High Functioning Autism Spectrum Disorder.

ABSTRACT:

Purpose

Autism spectrum disorder (ASD) is a neurodevelopmental disorder characterized by social communication impairments and repetitive behaviors or restricted interests. Impaired pragmatic language comprehension is a universal feature in individuals with ASD. However, the underlying neural basis of pragmatic language is poorly understood. In the present study, we examined neural activation patterns associated with impaired pragmatic language comprehension in ASD, compared to typically developing children (TDC).

Materials and methods

Functional magnetic resonance imaging (fMRI) was applied to 15 children with ASD and 18 TDC using the Korean pragmatic language task.

Results

Children with ASD were less accurate than TDC at comprehending idioms, particularly when they w

SUBMITTER: Kim N 

PROVIDER: S-EPMC6082980 | biostudies-literature | 2018 Sep

REPOSITORIES: biostudies-literature