Time-Dependent Finite Element Analysis of In Vivo Electrochemotherapy Treatment.

ABSTRACT: Electrochemotherapy and irreversible electroporation are gaining importance in clinical practice for the treatment of solid tumors. For successful treatment, it is extremely important that the coverage and exposure time of the treated tumor to the electric field are within the specified range. In order to ensure successful coverage of the entire target volume with sufficiently strong electric fields, numerical treatment planning has been proposed and its use has also been demonstrated in practice. Most of numerical models in treatment planning are based on charge conservation equation and are not able to provide time course of electric current, electrical conductivity, or electric field distribution changes established in the tissue during pulse delivery. Recently, a model based on inverse

SUBMITTER: Pintar M 

PROVIDER: S-EPMC6083743 | biostudies-literature | 2018 Jan

REPOSITORIES: biostudies-literature