Neurodevelopmental changes in the relationship between stress perception and prefrontal-amygdala functional circuitry.

ABSTRACT: Our brain during distinct developmental phases may show differential responses to perceived psychological stress, yet existing research specifically examining neurodevelopmental changes in stress processing is scarce. To fill in this research gap, this functional magnetic resonance imaging (fMRI) study examined the relationship between perceived stress and resting-state neural connectivity patterns among 67 healthy volunteers belonging to three age groups (adolescents, young adults and adults), who were supposed to be at separate neurodevelopmental phases and exhibit different affect regulatory processes in the brain. While the groups showed no significant difference in self-reported general perceived stress levels, the functional connectivity between amygdala and ventromedial prefrontal c

SUBMITTER: Wu J 

PROVIDER: S-EPMC6084015 | biostudies-literature | 2018

REPOSITORIES: biostudies-literature