Sensory modulation dysfunction is associated with Complex Regional Pain Syndrome.

ABSTRACT:

Objective

Complex Regional Pain Syndrome (CRPS), a chronic pain condition, develops mainly after limb trauma and severely inhibits function. While early diagnosis is essential, factors for CRPS onset are elusive. Therefore, identifying those at risk is crucial. Sensory modulation dysfunction (SMD), affects the capacity to regulate responses to sensory input in a graded and adaptive manner and was found associated with hyperalgesia in otherwise healthy individuals, suggestive of altered pain processing.

Aim

To test SMD as a potential risk factor for CRPS.

Methods

In this cross-sectional study, forty-four individuals with CRPS (29.9±11 years, 27 men) and 204 healthy controls (27.4±3.7 years, 105 men) completed the Sensory Responsiveness Questionnaire-Intensity Scale (SR

SUBMITTER: Bar-Shalita T 

PROVIDER: S-EPMC6084887 | biostudies-literature | 2018

REPOSITORIES: biostudies-literature