Risk factors for retinal microvascular impairment in type 2 diabetic patients without diabetic retinopathy.

ABSTRACT:

Objectives

To determine the risk factors for retinal microvascular impairment on optical coherence tomography angiography (OCT-A) in type 2 diabetic patients without clinical diabetic retinopathy (DR).

Methods

This retrospective and cross-sectional study enrolled 74 diabetic patients without clinically evident DR for the study group and 34 healthy subjects for the control group. OCT-A parameters were measured to determine vascular density (VD) and the foveal avascular zone (FAZ) size in the superficial and deep capillary plexuses (SCP/DCP) of the retina. Clinical data were collected on sex, age, diabetes duration, hemoglobin A1c (HbA1c), hypertension, dyslipidemia, low-density lipoprotein cholesterol (LDL-C), estimated glomerular filtration rate (eGFR) and smoking status. Mu

SUBMITTER: Lee DH 

PROVIDER: S-EPMC6084984 | biostudies-literature | 2018

REPOSITORIES: biostudies-literature