Characteristics of tree nut challenges in tree nut allergic and tree nut sensitized individuals.

ABSTRACT:

Background

Characteristics and outcomes of tree nut (TN) oral food challenges (OFCs) in patients with TN allergy or sensitization alone are poorly studied.

Objective

To determine the relation between TN sensitization levels and OFC outcomes.

Methods

Open TN OFCs performed from 2007 through 2015 at a referral center were analyzed to compare outcome based on skin prick test (SPT) wheal size, food-specific immunoglobulin E (sIgE), peanut co-allergy, and TN sensitization only vs TN allergy with sensitization to other TNs. Delayed OFC was defined as longer than 12 months from the time of an sIgE level lower than 2 kUA/L.

Results

Overall passage rate was 86% for 156 TN OFCs in 109 patients (54 almond, 28 cashew, 27 walnut, 18 hazelnut, 14 pecan, 13 pistachio, and 2 B

SUBMITTER: Couch C 

PROVIDER: S-EPMC6085138 | biostudies-literature | 2017 May

REPOSITORIES: biostudies-literature