Neonatal autonomic function after pregnancy complications and early cardiovascular development.

ABSTRACT:

Background

Heart rate variability (HRV) has emerged as a predictor of later cardiac risk. This study tested whether pregnancy complications that may have long-term offspring cardiac sequelae are associated with differences in HRV at birth, and whether these HRV differences identify abnormal cardiovascular development in the postnatal period.

Methods

Ninety-eight sleeping neonates had 5-min electrocardiogram recordings at birth. Standard time and frequency domain parameters were calculated and related to cardiovascular measures at birth and 3 months of age.

Results

Increasing prematurity, but not maternal hypertension or growth restriction, was associated with decreased HRV at birth, as demonstrated by a lower root mean square of the difference between adjacent NN inte

SUBMITTER: Aye CYL 

PROVIDER: S-EPMC6086328 | biostudies-literature | 2018 Jul

REPOSITORIES: biostudies-literature