Ontology highlight
ABSTRACT:
SUBMITTER: Davie K
PROVIDER: S-EPMC6086935 | biostudies-literature | 2018 Aug
REPOSITORIES: biostudies-literature
Cell 20180618 4
The diversity of cell types and regulatory states in the brain, and how these change during aging, remains largely unknown. We present a single-cell transcriptome atlas of the entire adult Drosophila melanogaster brain sampled across its lifespan. Cell clustering identified 87 initial cell clusters that are further subclustered and validated by targeted cell-sorting. Our data show high granularity and identify a wide range of cell types. Gene network analyses using SCENIC revealed regulatory het ...[more]