Analysis of clinical benefit, harms, and cost-effectiveness of screening women for abdominal aortic aneurysm.

ABSTRACT:

Background

A third of deaths in the UK from ruptured abdominal aortic aneurysm (AAA) are in women. In men, national screening programmes reduce deaths from AAA and are cost-effective. The benefits, harms, and cost-effectiveness in offering a similar programme to women have not been formally assessed, and this was the aim of this study.

Methods

We developed a decision model to assess predefined outcomes of death caused by AAA, life years, quality-adjusted life years, costs, and the incremental cost-effectiveness ratio for a population of women invited to AAA screening versus a population who were not invited to screening. A discrete event simulation model was set up for AAA screening, surveillance, and intervention. Relevant women-specific parameters were obtained from source

SUBMITTER: Sweeting MJ 

PROVIDER: S-EPMC6087711 | biostudies-literature | 2018 Aug

REPOSITORIES: biostudies-literature