Influence of age on radiomic features in ¹⁸F-FDG PET in normal breast tissue and in breast cancer tumors.

ABSTRACT:

Background

To help interpret measurements in breast tissue and breast tumors from ¹⁸F-FDG PET scans, we studied the influence of age in measurements of PET parameters in normal breast tissue and in a breast cancer (BC) population.

Results

522 women were included: 331 pts without history of BC (B-VOI) and 191 patients with BC (T-VOI). In B-VOI, there were significant differences between all age groups for Standardized Uptake Values (SUVs) and for 12 textural indices (TI) whereas histogram-based indices (HBI) did not vary between age groups. SUV values decreased over time whereas Homogeneity increased. We had a total of 210 T-VOI and no significant differences were found according to the histological type between 190 ductal carcinoma and 18 lobular carcinoma. Conver

SUBMITTER: Boughdad S 

PROVIDER: S-EPMC6089391 | biostudies-literature | 2018 Jul

REPOSITORIES: biostudies-literature